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Article

Novel Genes Associated With Atrial Fibrillation and the Predictive Models for AF Incorporating Polygenic Risk Score and PheWAS-Derived Risk Factors.

The Canadian journal of cardiology - 1 Nov 2024

Chen Shih-Yin, Chen Yu-Chia, Liu Ting-Yuan, Chang Kuan-Cheng, Chang Shih-Sheng, Wu Ning, Lee Wu Donald, Dunlap Rylee Kay, Chan Chia-Jung, Yang Jai-Sing, Liao Chi Chou, Tsai Fuu-Jen

Abstract excerpt

BACKGROUND: Atrial fibrillation (AF), the most common atrial arrhythmia, presents with varied clinical manifestations. Despite the identification of genetic loci associated with AF, particularly in specific populations, research within Asian ethnicities remains limited. In this study we aimed to develop predictive models for AF using AF-associated single-nucleotide polymorphisms (SNPs) from a genome-wide...

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PMID: 39142603
DOI: 10.1016/j.cjca.2024.07.029

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