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Article

Polygenic risk scores in atrial fibrillation: Associations and clinical utility in disease prediction.

Heart rhythm - 1 Jun 2024

Gibson Joel T, Rudd James H F

Abstract excerpt

Atrial fibrillation (AF) is a common heart arrhythmia and a major cause of cardioembolic stroke. Therefore, accurate prediction is desirable to allow high-risk individuals to be identified early and their risk lowered before complications arise. Polygenic risk scores (PRSs) have become a popular method of quantifying aggregated genetic risk from common variants, but their clinical value in AF remains uncertain....

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Identifiers

PMID: 38336192
DOI: 10.1016/j.hrthm.2024.02.006

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