Article
Genomic Variants in NEURL, GJA1 and CUX2 Significantly Increase Genetic Susceptibility to Atrial Fibrillation.
Scientific reports - 19 Feb 2018
Wang Pengxia, Qin Weixi, Wang Pengyun, Huang Yufeng, Liu Ying, Zhang Rongfeng, Li Sisi, Yang Qin, Wang Xiaojing, Chen Feifei, Liu Jingqiu, Yang Bo, Cheng Xiang, Liao Yuhua, Wu Yanxia, Ke Tie, Tu Xin, Ren Xiang, Yang Yanzong, Xia Yunlong, Luo Xiaoping, Liu Mugen, Li He, Liu Jingyu, Xiao Yi, Chen Qiuyun, Xu Chengqi, Wang Qing K
Abstract excerpt
Atrial fibrillation (AF) is the most common arrhythmia. In 2014, two new meta-GWAS identified 5 AF loci, including the NEURL locus, GJA1 locus, CAND2 locus, and TBX5 locus in the European ancestry populations and the NEURL locus and CUX2 locus in a Japanese population. The TBX5 locus for AF was reported by us in 2013 in the Chinese population. Here we assessed the association between AF and SNPs in the NEURL,...
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