Article
Novel genetic markers associate with atrial fibrillation risk in Europeans and Japanese.
Journal of the American College of Cardiology - 1 Apr 2014
Lubitz Steven A, Lunetta Kathryn L, Lin Honghuang, Arking Dan E, Trompet Stella, Li Guo, Krijthe Bouwe P, Chasman Daniel I, Barnard John, Kleber Marcus E, Dörr Marcus, Ozaki Kouichi, Smith Albert V, Müller-Nurasyid Martina, Walter Stefan, Agarwal Sunil K, Bis Joshua C, Brody Jennifer A, Chen Lin Y, Everett Brendan M, Ford Ian, Franco Oscar H, Harris Tamara B, Hofman Albert, Kääb Stefan, Mahida Saagar, Kathiresan Sekar, Kubo Michiaki, Launer Lenore J, MacFarlane Peter W, Magnani Jared W, McKnight Barbara, McManus David D, Peters Annette, Psaty Bruce M, Rose Lynda M, Rotter Jerome I, Silbernagel Guenther, Smith Jonathan D, Sotoodehnia Nona, Stott David J, Taylor Kent D, Tomaschitz Andreas, Tsunoda Tatsuhiko, Uitterlinden Andre G, Van Wagoner David R, Völker Uwe, Völzke Henry, Murabito Joanne M, Sinner Moritz F, Gudnason Vilmundur, Felix Stephan B, März Winfried, Chung Mina, Albert Christine M, Stricker Bruno H, Tanaka Toshihiro, Heckbert Susan R, Jukema J Wouter, Alonso Alvaro, Benjamin Emelia J, Ellinor Patrick T
Abstract excerpt
OBJECTIVES: This study sought to identify nonredundant atrial fibrillation (AF) genetic susceptibility signals and examine their cumulative relations with AF risk. BACKGROUND: AF-associated loci span broad genomic regions that may contain multiple susceptibility signals. Whether multiple signals exist at AF loci has not been systematically explored. METHODS: We performed association testing conditioned on the...
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