Article
Identification of six new genetic loci associated with atrial fibrillation in the Japanese population.
Nature genetics - 1 Jun 2017
Low Siew-Kee, Takahashi Atsushi, Ebana Yusuke, Ozaki Kouichi, Christophersen Ingrid E, Ellinor Patrick T, Ogishima Soichi, Yamamoto Masayuki, Satoh Mamoru, Sasaki Makoto, Yamaji Taiki, Iwasaki Motoki, Tsugane Shoichiro, Tanaka Keitaro, Naito Mariko, Wakai Kenji, Tanaka Hideo, Furukawa Tetsushi, Kubo Michiaki, Ito Kaoru, Kamatani Yoichiro, Tanaka Toshihiro
Abstract excerpt
Atrial fibrillation is the most common cardiac arrhythmia and leads to stroke. To investigate genetic loci associated with atrial fibrillation in the Japanese population, we performed a genome-wide association study (GWAS) that included 8,180 atrial fibrillation cases and 28,612 controls with follow-up in an additional 3,120 cases and 125,064 controls. We replicated previously reported loci and identified six new...
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