Article
Motor learning and COMT Val158met polymorphism: Analyses of oculomotor behavior and corticocortical communication.
Neurobiology of learning and memory - 1 Feb 2020
Nogueira Nathálya Gardênia de Holanda Marinho, Miranda Débora Marques de, Albuquerque Maicon Rodrigues, Ferreira Bárbara de Paula, Batista Marco Túlio Silva, Parma Juliana Otoni, Apolinário-Souza Tércio, Bicalho Lucas Eduardo Antunes, Ugrinowitsch Herbert, Lage Guilherme Menezes
Abstract excerpt
Differences in motor learning can be partially explained by differences in genotype. The catechol-O-methyltransferase (COMT) Val158Met polymorphism regulates the dopamine (DA) availability in the prefrontal cortex modulating motor learning and performance. Given the differences in tonic and phasic DA transmission, this study aimed to investigate whether the greater cognitive flexibility associated with the Val...
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