Article
Association of COMT val158met and DRD2 G>T genetic polymorphisms with individual differences in motor learning and performance in female young adults.
Journal of neurophysiology - 1 Feb 2014
Noohi Fatemeh, Boyden Nate B, Kwak Youngbin, Humfleet Jennifer, Burke David T, Müller Martijn L T M, Bohnen Nico I, Seidler Rachael D
Abstract excerpt
Individuals learn new skills at different rates. Given the involvement of corticostriatal pathways in some types of learning, variations in dopaminergic transmission may contribute to these individual differences. Genetic polymorphisms of the catechol-O-methyltransferase (COMT) enzyme and dopamine receptor D2 (DRD2) genes partially determine cortical and striatal dopamine availability, respectively. Individuals...
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