Article
Effect of catechol-O-methyltransferase-val158met-polymorphism on the automatization of motor skills - a post hoc view on an experimental data.
Behavioural brain research - 1 Jun 2014
Krause Daniel, Beck Frieder, Agethen Manfred, Blischke Klaus
Abstract excerpt
The purpose of this study was to evaluate if the catechol-O-methyltransferase-val158met (COMT)-polymorphism, which is known to affect prefrontal dopaminergic metabolism, affects the automatization of motor skills. Twenty-two participants volunteered for gene analysis after they had participated in experiments in which they practiced a single-joint arm movement sequence 460-760 times under different feedback...
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