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Article

Individual differences in learning and decision-making: the role of COMT Val158Met polymorphism in transitive inference.

Experimental brain research - 26 Feb 2026

Paul Ann, Segreti Mariella, Marc Isabel Beatrice, Fiorenza Maria Teresa, Canterini Sonia, Ramawat Surabhi, Bardella Giampiero, Pani Pierpaolo, Ferraina Stefano, Brunamonti Emiliano

Abstract excerpt

Understanding the ordinal relationships between items organized hierarchically requires constructing a rank order supporting decision-making between options. This process depends on the ability to learn reciprocal relationships and to select the best option available when making a choice. In such forms of decision-making, the prefrontal cortex (PFC) plays a crucial role in encoding the relative value of...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 41746371
DOI: 10.1007/s00221-026-07247-4
PMCID: PMC12946361

Genes

COMT

Variants

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026.

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