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Article

Mechanisms underlying reduced weight gain in intestinal fatty acid-binding protein (IFABP) null mice.

American journal of physiology. Gastrointestinal and liver physiology - 1 Mar 2020

Lackey Atreju I, Chen Tina, Zhou Yin X, Bottasso Arias Natalia M, Doran Justine M, Zacharisen Sophia M, Gajda Angela M, Jonsson William O, Córsico Betina, Anthony Tracy G, Joseph Laurie B, Storch Judith

Abstract excerpt

Intestinal-fatty acid binding protein (IFABP; FABP2) is a 15-kDa intracellular protein abundantly present in the cytosol of the small intestinal (SI) enterocyte. High-fat (HF) feeding of IFABP-/- mice resulted in reduced weight gain and fat mass relative to wild-type (WT) mice. Here, we examined intestinal properties that may underlie the observed lean phenotype of high fat-fed IFABP-/- mice. No alterations in...

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Identifiers

PMID: 31905021
DOI: 10.1152/ajpgi.00120.2019
PMCID: PMC7099495

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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