Article

Novel hyperplastic expansion of white adipose tissue underlies the metabolically healthy obese phenotype of male LFABP null mice

2025-04-08

Abstract excerpt

Obesity is an important risk factor for the development of metabolic syndrome disorders. We previously showed that the liver fatty acid-binding protein null mouse (LFABP −/− ) becomes obese upon high-fat diet (HFD) feeding but remains metabolically healthy. Here we find that the obese LFABP −/− mouse increases subcutaneous adipose tissue (SAT) mass by markedly increasing the number rather than the size of adipoc...

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Literature Corpus work: 2bd70d53-935f-5db4-b6e8-70c9b8a5e2ab
DOI: 10.1101/2025.04.07.647661

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