Article
Gut Microbiota and Phenotypic Changes Induced by Ablation of Liver- and Intestinal-Type Fatty Acid-Binding Proteins.
Nutrients - 22 Apr 2022
Wu Guojun, Tawfeeq Hiba R, Lackey Atreju I, Zhou Yinxiu, Sifnakis Zoe, Zacharisen Sophia M, Xu Heli, Doran Justine M, Sampath Harini, Zhao Liping, Lam Yan Y, Storch Judith
Abstract excerpt
Intestinal fatty acid-binding protein (IFABP; FABP2) and liver fatty acid-binding protein (LFABP; FABP1) are small intracellular lipid-binding proteins. Deficiency of either of these proteins in mice leads to differential changes in intestinal lipid transport and metabolism, and to markedly divergent changes in whole-body energy homeostasis. The gut microbiota has been reported to play a pivotal role in metabolic...
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