Article
Loss of the acyl-CoA binding protein (Acbp) results in fatty acid metabolism abnormalities in mouse hair and skin.
The Journal of investigative dermatology - 1 Jan 2007
Lee Lance, DeBono C Anthony, Campagna Dean R, Young David C, Moody D Branch, Fleming Mark D
Abstract excerpt
Proper fatty acid metabolism is critical for hair and skin development and maintenance. The acyl-CoA binding protein (Acbp) is a widely expressed protein that binds long-chain fatty acyl-CoA esters and plays a role in fatty acyl-CoA transport and pool formation. However, loss of function of Acbp in the whole animal has not been investigated. Here, we show that deletion of Acbp in mouse results in sebocyte...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.