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Article

Clonal reconstruction from time course genomic sequencing data.

BMC genomics - 30 Dec 2019

Ismail Wazim Mohammed, Tang Haixu

Abstract excerpt

BACKGROUND: Bacterial cells during many replication cycles accumulate spontaneous mutations, which result in the birth of novel clones. As a result of this clonal expansion, an evolving bacterial population has different clonal composition over time, as revealed in the long-term evolution experiments (LTEEs). Accurately inferring the haplotypes of novel clones as well as the clonal frequencies and the clonal...

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Identifiers

PMID: 31888455
DOI: 10.1186/s12864-019-6328-3
PMCID: PMC6936074

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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