Article

Theoretical estimates on the expected number of mutations for reconstructing clonal lineage trees

2025-11-21

Abstract excerpt

Phylogenetics, like many subdisciplines of computational biology, faces a growing challenge of dealing with increasingly large and complicated data sets that have been enabled by ever-improving technologies for sequencing. The issue is particularly acute for studies of somatic evolution, such as of single-cell populations in cancers, where vast single-cell data sets may now identify hundreds of thousands of geneti...

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Literature Corpus work: 9223fd84-f5d9-5969-b737-d0025955f197
DOI: 10.1101/2025.11.20.689642

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