Article
Performance of a novel Next Generation Sequencing circulating tumor DNA (ctDNA) platform for the evaluation of samples from patients with metastatic breast cancer (MBC).
Critical reviews in oncology/hematology - 1 Jan 2020
Gerratana Lorenzo, Zhang Qiang, Shah Ami Naimish, Davis Andrew Adam, Zhang Youbin, Wehbe Firas, Qiang Wenan, Flaum Lisa, Finkelman Brian Steven, Gradishar William John, Platanias Leonidas C, Behdad Amir, Cristofanilli Massimo
Abstract excerpt
Circulating tumor DNA (ctDNA) is gaining momentum as sensitive diagnostic tool for advanced disease characterization because of its ability both to capture the tumor's heterogeneity and its dynamic adaptations. However, the consistency between all the available platforms is still debated. The aim of the study was to explore the performance of the novel diagnostic NGS platform PredicinePLUS™ and to compare its...
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