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Circulating tumour DNA testing in metastatic breast cancer: Integration with tissue testing.

Cytopathology : official journal of the British Society for Clinical Cytology - 1 Nov 2023

Ranghiero Alberto, Frascarelli Chiara, Cursano Giulia, Pescia Carlo, Ivanova Mariia, Vacirca Davide, Rappa Alessandra, Taormina Sergio Vincenzo, Barberis Massimo, Fusco Nicola, Rocco Elena Guerini, Venetis Konstantinos

Abstract excerpt

Breast cancer biomarker profiling predominantly relies on tissue testing (surgical and/or biopsy samples). However, the field of liquid biopsy, particularly the analysis of circulating tumour DNA (ctDNA), has witnessed remarkable progress and continues to evolve rapidly. The incorporation of ctDNA-based testing into clinical practice is creating new opportunities for patients with metastatic breast cancer (MBC)....

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PMID: 37640801
DOI: 10.1111/cyt.13295

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