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The applications of plasma cell-free DNA in cancer detection: Implications in the management of breast cancer patients.

Critical reviews in oncology/hematology - 1 Jul 2022

Igari Fumie, Tanaka Hisashi, Giuliano Armando E

Abstract excerpt

Liquid biopsy probes DNA, RNA, and proteins in body fluids for cancer detection and is one of the most rapidly developing areas in oncology. Tumor-derived DNA (circulating tumor DNA, ctDNA) in the context of cell-free DNA (cfDNA) in blood has been the main target for its potential utilities in cancer detection. Liquid biopsy can report tumor burden in real-time without invasive interventions, and would be...

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PMID: 35618229
DOI: 10.1016/j.critrevonc.2022.103725

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