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Article

The dynamic range of circulating tumor DNA in metastatic breast cancer.

Breast cancer research : BCR - 9 Aug 2014

Heidary Maryam, Auer Martina, Ulz Peter, Heitzer Ellen, Petru Edgar, Gasch Christin, Riethdorf Sabine, Mauermann Oliver, Lafer Ingrid, Pristauz Gunda, Lax Sigurd, Pantel Klaus, Geigl Jochen B, Speicher Michael R

Abstract excerpt

INTRODUCTION: The management of metastatic breast cancer needs improvement. As clinical evaluation is not very accurate in determining the progression of disease, the analysis of circulating tumor DNA (ctDNA) has evolved to a promising noninvasive marker of disease evolution. Indeed, ctDNA was reported to represent a highly sensitive biomarker of metastatic cancer disease directly reflecting tumor burden and...

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Identifiers

PMID: 25107527
DOI: 10.1186/s13058-014-0421-y
PMCID: PMC4303230

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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