Article
Clinical applications of circulating tumor DNA in monitoring breast cancer drug resistance.
Future oncology (London, England) - 1 Dec 2020
Liu Yang, Du Qian, Sun Dan, Han Ruiying, Teng Mengmeng, Chen Siying, You Haisheng, Dong Yalin
Abstract excerpt
Breast cancer is one of the leading causes of cancer-related deaths in women worldwide. Unfortunately, treatments often fail because of the development of drug resistance, the underlying mechanisms of which remain unclear. Circulating tumor DNA (ctDNA) is free DNA released into the blood by necrosis, apoptosis or direct secretion by tumor cells. In contrast to repeated, highly invasive tumor biopsies, ctDNA...
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