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Clinical application of circulating tumor DNA in breast cancer.

Journal of cancer research and clinical oncology - 1 May 2021

Chan Jeffrey Chun Hin, Chow James Chung Hang, Ho Connie Hoi Man, Tsui Therese Yue Man, Cho William C

Abstract excerpt

BACKGROUND: The recent advancement in massively parallel sequencing technologies has empowered liquid biopsies, in particular circulating tumor DNA (ctDNA) analysis, to be the new paradigm in personalized cancer management. Plasma ctDNA detection overcomes the current limitations in tumor tissue procurement and serves as a convenient and non-invasive method to capture tumor heterogeneity and genetic evolution...

Topics

Breast Neoplasms
Circulating Tumor DNA
Female
Humans
Liquid Biopsy
Mutation

Source

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Identifiers

PMID: 33760943
DOI: 10.1007/s00432-021-03588-5

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 31 Aug 2026.

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