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Strategies for improving detection of circulating tumor DNA using next generation sequencing.

Cancer treatment reviews - 1 Sept 2023

Tébar-Martínez Roberto, Martín-Arana Jorge, Gimeno-Valiente Francisco, Tarazona Noelia, Rentero-Garrido Pilar, Cervantes Andrés

Abstract excerpt

Cancer has become a global health issue and liquid biopsy has emerged as a non-invasive tool for various applications. In cancer, circulating tumor DNA (ctDNA) can be detected from cell-free DNA (cfDNA) obtained from plasma and has potential for early diagnosis, treatment, resistance, minimal residual disease detection, and tumoral heterogeneity identification. However, the low frequency of ctDNA requires...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 37390697
DOI: 10.1016/j.ctrv.2023.102595

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026.

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