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Ongoing Clinical Trials and Future Research Scenarios of Circulating Tumor DNA for the Treatment of Metastatic Colorectal Cancer.

Clinical colorectal cancer - 1 Dec 2024

Roazzi Laura, Patelli Giorgio, Bencardino Katia Bruna, Amatu Alessio, Bonazzina Erica, Tosi Federica, Amoruso Brunella, Bombelli Anna, Mariano Sara, Stabile Stefano, Porta Camillo, Siena Salvatore, Sartore-Bianchi Andrea

Abstract excerpt

Liquid biopsy using circulating tumor DNA (ctDNA) has emerged as a minimally invasive, timely approach to provide molecular diagnosis and monitor tumor evolution in patients with cancer. Since the molecular landscape of metastatic colorectal cancer (mCRC) is substantially heterogeneous and dynamic over space and time, ctDNA holds significant advantages as a biomarker for this disease. Numerous studies have...

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Identifiers

PMID: 38519391
DOI: 10.1016/j.clcc.2024.02.001

Genes

BRAF
EGFR

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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