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Targeted Next-Generation Sequencing of Circulating Tumor DNA Mutations among Metastatic Breast Cancer Patients.

Current oncology (Toronto, Ont.) - 24 Jun 2021

Sun Min-Ying, Lin Fang-Qin, Chen Lu-Jia, Li Hong, Lin Wei-Quan, Du Hong-Yan, Yang Xue-Xi, Li Ming

Abstract excerpt

Liquid biopsy through the detection of circulating tumor DNA (ctDNA) has potential advantages in cancer monitoring and prediction. However, most previous studies in this area were performed with a few hotspot genes, single time point detection, or insufficient sequencing depth. In this study, we performed targeted next-generation sequencing (NGS) with a customized panel in metastatic breast cancer (MBC) patients....

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Source

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Identifiers

PMID: 34202466
DOI: 10.3390/curroncol28040214
PMCID: PMC8293138

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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