Article

A deoxynucleoside triphosphate triphosphohydrolase promotes cell cycle progression in <i>Caulobacter crescentus</i>

2024-04-26

Abstract excerpt

Intracellular pools of deoxynucleoside triphosphates (dNTPs) are strictly maintained throughout the cell cycle to ensure accurate and efficient DNA replication. DNA synthesis requires an abundance of dNTPs, but elevated dNTP concentrations in nonreplicating cells delay entry into S phase. Enzymes known as deoxyguanosine triphosphate triphosphohydrolases (Dgts) hydrolyze dNTPs into deoxynucleosides and triphosphate...

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Identifiers and source

Literature Corpus work: 9cf3469f-f241-5759-8ad4-0b4fa18a418b
DOI: 10.1101/2024.04.25.591158

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