Article
The Caulobacter crescentus ctrA P1 promoter is essential for the coordination of cell cycle events that prevent the overinitiation of DNA replication.
Microbiology (Reading, England) - 1 Oct 2012
Schredl Alexander T, Perez Mora Yannet G, Herrera Anabel, Cuajungco Math P, Murray Sean R
Abstract excerpt
The master regulator CtrA oscillates during the Caulobacter cell cycle due to temporally regulated proteolysis and transcription. It is proteolysed during the G1-S transition and reaccumulates in predivisional cells as a result of transcription from two sequentially activated promoters, P1 and P2. CtrA reinforces its own synthesis by directly mediating the activation of P2 concurrently with repression of P1. To...
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