Article
A DNA damage checkpoint in Caulobacter crescentus inhibits cell division through a direct interaction with FtsW.
Genes & development - 15 Jun 2011
Modell Joshua W, Hopkins Alexander C, Laub Michael T
Abstract excerpt
Following DNA damage, cells typically delay cell cycle progression and inhibit cell division until their chromosomes have been repaired. The bacterial checkpoint systems responsible for these DNA damage responses are incompletely understood. Here, we show that Caulobacter crescentus responds to DNA damage by coordinately inducing an SOS regulon and inhibiting the master regulator CtrA. Included in the SOS regulon...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
