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Article

wtest: an integrated R package for genetic epistasis testing.

BMC medical genomics - 24 Dec 2019

Sun Rui, Xia Xiaoxuan, Chong Ka Chun, Zee Benny Chung-Ying, Wu William Ka Kei, Wang Maggie Haitian

Abstract excerpt

BACKGROUND: With the increasing amount of high-throughput genomic sequencing data, there is a growing demand for a robust and flexible tool to perform interaction analysis. The identification of SNP-SNP, SNP-CpG, and higher order interactions helps explain the genetic etiology of human diseases, yet genome-wide analysis for interactions has been very challenging, due to the computational burden and a lack of...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Identifiers

PMID: 31874630
DOI: 10.1186/s12920-019-0638-9
PMCID: PMC6929460

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