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Article

Protocol for Construction of Genome-Wide Epistatic SNP Networks Using WISH-R Package.

Methods in molecular biology (Clifton, N.J.) - 1 Jan 2021

Kadarmideen Haja N, Carmelo Victor Adriano Okstoft

Abstract excerpt

Epistasis is the interaction between genes or genetic variants (such as Single Nucleotide Polymorphisms or SNPs) that influences a phenotype or a disease outcome. Statistically and biologically, significant evidence of epistatic loci for several traits and diseases is well known in human, animals, and plants. However, there is no straightforward way to compute a large number of pairwise epistasis among millions...

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PMID: 33733355
DOI: 10.1007/978-1-0716-0947-7_10

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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