Article

Fast and Accurate Exhaustive Higher-Order Epistasis Search with BitEpi

2019-11-29

Abstract excerpt

<h4>Motivation</h4> Complex genetic diseases may be modulated by a large number of epistatic interactions affecting a polygenic phenotype. Identifying these interactions is difficult due to computational complexity, especially in the case of higher-order interactions where more than two genomic variants are involved. <h4>Results</h4> In this paper, we present BitEpi, a fast and accurate method to test all possib...

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Literature Corpus work: 64dfcb00-3b5d-50a3-97ac-bfae084ca5de
DOI: 10.1101/858282

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