Article
Protocol for Epistasis Detection with Machine Learning Using GenEpi Package.
Methods in molecular biology (Clifton, N.J.) - 1 Jan 2021
Petinrin Olutomilayo Olayemi, Wong Ka-Chun
Abstract excerpt
To develop medical treatments and prevention, the association between disease and genetic variants needs to be identified. The main goal of genome-wide association study (GWAS) is to discover the underlying reason for vulnerability to disease and utilize this knowledge for the development of prevention and treatment against these diseases. Given the methods available to address the scientific problems involved in...
Topics
- Computational Biology
- Databases, Genetic
- Epistasis, Genetic
- Genetic Association Studies
- Genome, Human
- Genome-Wide Association Study
- Genotype
- Humans
- Machine Learning
- Phenotype
- Polymorphism, Single Nucleotide