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W-Test for Genetic Epistasis Testing.

Methods in molecular biology (Clifton, N.J.) - 1 Jan 2021

Sun Rui, Weng Haoyi, Wang Maggie Haitian

Abstract excerpt

The genetic epistasis effect has been widely acknowledged as an essential contributor to genetic variation in complex diseases. In this chapter, we introduce a powerful and efficient statistical method, called W-test, for genetic epistasis testing. A wtest R package is developed for the implementation of the W-test method, which provides various functions to measure the main effect, pairwise interaction,...

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PMID: 33733349
DOI: 10.1007/978-1-0716-0947-7_4

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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