Article
Prevalence of Inherited Mutations in Breast Cancer Predisposition Genes among Women in Uganda and Cameroon.
Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology - 1 Feb 2020
Adedokun Babatunde, Zheng Yonglan, Ndom Paul, Gakwaya Antony, Makumbi Timothy, Zhou Alicia Y, Yoshimatsu Toshio F, Rodriguez Alex, Madduri Ravi K, Foster Ian T, Sallam Aminah, Olopade Olufunmilayo I, Huo Dezheng
Abstract excerpt
BACKGROUND: Sub-Saharan Africa (SSA) has a high proportion of premenopausal hormone receptor negative breast cancer. Previous studies reported a strikingly high prevalence of germline mutations in BRCA1 and BRCA2 among Nigerian patients with breast cancer. It is unknown if this exists in other SSA countries. METHODS: Breast cancer cases, unselected for age at diagnosis and family history, were recruited from...
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