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Article

High prevalence of BRCA1 and BRCA2 mutations in unselected Nigerian breast cancer patients.

International journal of cancer - 1 Sept 2012

Fackenthal James D, Zhang Jing, Zhang Bifeng, Zheng Yonglan, Hagos Fitsum, Burrill Devin R, Niu Qun, Huo Dezheng, Sveen Walmy E, Ogundiran Temidayo, Adebamowo Clemet, Odetunde Abayomi, Falusi Adeyinka G, Olopade Olufunmilayo I

Abstract excerpt

Inherited mutations in the BRCA1 and BRCA2 genes are the strongest genetic predictors of breast cancer and are the primary causes of familial breast/ovarian cancer syndrome. The frequency, spectrum and penetrance of mutant BRCA1/BRCA2 alleles have been determined for several populations, but little information is available for populations of African ancestry, who suffer a disproportionate burden of early onset...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 22034289
DOI: 10.1002/ijc.27326

Genes

BRCA1
BRCA2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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