Article
Cancer genetic mutation prevalence in sub-Saharan Africa: A review of existing data.
Seminars in oncology - 1 Dec 2023
Shain Joshua, Michel Alissa, May Michael S, Qunaj Lindor, El-Sadr Wafaa, Chung Wendy K, Appelbaum Paul S, Jacobson Judith S, Justman Jessica, Neugut Alfred I
Abstract excerpt
BACKGROUND: Cancer represents a leading cause of death worldwide. Germline mutations in several genes increase the risk of developing several cancers, including cancers of the breast, ovary, pancreas, colorectum, and melanoma. An understanding of the population prevalence of pathogenic germline variants can be helpful in the design of public health interventions, such as genetic testing, which has downstream...
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