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Article

Germline sequence variants contributing to cancer susceptibility in South African breast cancer patients of African ancestry.

Scientific reports - 17 Jan 2022

Eygelaar Dewald, van Rensburg Elizabeth J, Joubert Fourie

Abstract excerpt

Since the discovery of the breast cancer susceptibility genes, BRCA1 and BRCA2, various other genes conferring an increased risk for breast cancer have been identified. Studies to evaluate sequence variants in cancer predisposition genes among women of African ancestry are limited and mostly focused on BRCA1 and BRCA2. To characterize germline sequence variants in cancer susceptibility genes, we analysed a cohort...

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Identifiers

PMID: 35039564
DOI: 10.1038/s41598-022-04791-1
PMCID: PMC8763903

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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