Mapping the Prevalence of BRCA1 and BRCA2 Mutations in Hereditary Breast and Ovarian Cancer Across Africa: A Systematic Review and Meta-Analysis.

doi:10.31557/APJCP.2026.27.8.2761

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Article

Mapping the Prevalence of BRCA1 and BRCA2 Mutations in Hereditary Breast and Ovarian Cancer Across Africa: A Systematic Review and Meta-Analysis.

Asian Pacific journal of cancer prevention : APJCP - 1 Aug 2026

Milambo Jean Paul Muambangu, Chitha Wilson Wezile

Abstract excerpt

BACKGROUND: BRCA1 and BRCA2 gene mutations are major contributors to hereditary breast and ovarian cancer syndrome (HBOC). While mutation prevalence has been well-characterized in high-income countries, African populations remain underrepresented in genomics cancer research. Accurate prevalence data are essential for informing targeted screening, counselling, and personalized treatment strategies across the...

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PMID: 42663196
DOI: 10.31557/APJCP.2026.27.8.2761

Genes

BRCA1
BRCA2

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 15 Sept 2026.