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Article

Inherited predisposition to breast cancer among African American women.

Breast cancer research and treatment - 1 Jan 2015

Churpek Jane E, Walsh Tom, Zheng Yonglan, Moton Zakiya, Thornton Anne M, Lee Ming K, Casadei Silvia, Watts Amanda, Neistadt Barbara, Churpek Matthew M, Huo Dezheng, Zvosec Cecilia, Liu Fang, Niu Qun, Marquez Rafael, Zhang Jing, Fackenthal James, King Mary-Claire, Olopade Olufunmilayo I

Abstract excerpt

African Americans have a disproportionate burden of aggressive young-onset breast cancer. Genomic testing for inherited predisposition to breast cancer is increasingly common in clinical practice, but comprehensive mutation profiles remain unknown for most minority populations. We evaluated 289 patients who self-identified as African American with primary invasive breast cancer and with personal or family cancer...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 25428789
DOI: 10.1007/s10549-014-3195-0
PMCID: PMC4298662

Genes

BRCA1
BRCA2
ATM
BARD1
CHEK2
PALB2
PTEN

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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