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Article

Correlations between macrophage polarization and osteoinduction of porous calcium phosphate ceramics.

Acta biomaterialia - 1 Feb 2020

Chen Xuening, Wang Menglu, Chen Fuying, Wang Jing, Li Xiangfeng, Liang Jie, Fan Yujiang, Xiao Yumei, Zhang Xingdong

Abstract excerpt

The host immune response is critical for in situ osteogenesis, but correlations between local inflammatory reactions and biomaterial osteoinduction are still poorly understood. This study used a murine intramuscular implantation model to demonstrate that calcium phosphate ceramics with different phase compositions exhibited divergent osteoinductivities. The osteoinductive potential of each ceramic was closely...

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Identifiers

PMID: 31857257
DOI: 10.1016/j.actbio.2019.12.019

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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