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Beta-tricalcium phosphate promotes osteogenic differentiation of bone marrow-derived mesenchymal stem cells through macrophages.

Biomedical materials (Bristol, England) - 18 Feb 2021

Zheng Mengting, Weng Mengjia, Zhang Xiaoyu, Li Ruomei, Tong Qian, Chen Zhenqi

Abstract excerpt

Macrophages are vital regulators of skeletal remodeling and osseous repair. Beta-tricalcium phosphate (β-TCP) is a synthetic ceramic biomaterial that has shown promise as bone substitute. However, whether and how β-TCP affects osteogenesis-related responses of macrophages has rarely been studied. The aims of this study were to explore (a) the effects of β-TCP on osteogenic differentiation of bone marrow-derived...

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PMID: 33445164
DOI: 10.1088/1748-605X/abdbdc

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