Article
Coupling between macrophage phenotype, angiogenesis and bone formation by calcium phosphates.
Materials science & engineering. C, Materials for biological applications - 1 Mar 2021
Duan Rongquan, Zhang Yang, van Dijk Luuk, Barbieri Davide, van den Beucken Jeroen, Yuan Huipin, de Bruijn Joost
Abstract excerpt
The ability of calcium phosphate (CaP) materials to induce bone formation varies with their physicochemical properties, with surface topography as one of the most crucial triggers. In view of the natural wound healing processes (e.g., inflammation, angiogenesis, tissue formation and remodeling) initiated after surgical implantation, we here comparatively investigated the biological cascades occurring upon ectopic...
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