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Article

[Reconstruction of tumor clonal haplotypes based on an improved spanning algorithm].

Nan fang yi ke da xue xue bao = Journal of Southern Medical University - 30 Nov 2019

Geng Yu, Zhao Zhongmeng, Liu Jianye

Abstract excerpt

OBJECTIVE: To reconstruct tumor clonal haplotypes based on the third-generation sequencing data to effectively identify tumor heterogeneity. METHODS: We developed an algorithm for extracting somatic mutational event from the mixed tumor data and determining the connection weight of each somatic cell mutation site through the probability function. A reconstruction algorithm of the haplotype was designed based on...

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Identifiers

PMID: 31852653
DOI: 10.12122/j.issn.1673-4254.2019.11.04
PMCID: PMC6926082

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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