Article
[Application and clinical study of clonal heterogeneity analysis in acute myeloid leukemia].
Zhonghua xue ye xue za zhi = Zhonghua xueyexue zazhi - 14 Jun 2020
Lyu X D, Guo Z, Li Y W, Hu J Y, Fan R H, Song Y P
Abstract excerpt
Objective: This study aimed to explore the characteristics and clinical value of clonal heterogeneity in acute myeloid leukemia (AML) . Method: A high-throughput sequencing was carried out to detect 68 related genes in 465 AML patients. Clonal heterogeneity was analyzed based on variant allele frequency (VAF) and flow cytometry results combined with clinical data. Results: Gene mutations were discovered in 338...
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