Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Neoantigen Fitness Model Predicts Lower Immune Recognition of Cutaneous Squamous Cell Carcinomas Than Actinic Keratoses.

Frontiers in immunology - 1 Jan 2019

Borden Elizabeth S, Kang Paul, Natri Heini M, Phung Tanya N, Wilson Melissa A, Buetow Kenneth H, Hastings Karen Taraszka

Abstract excerpt

A low percentage of actinic keratoses progress to develop into cutaneous squamous cell carcinoma. The immune mechanisms that successfully control or eliminate the majority of actinic keratoses and the mechanisms of immune escape by invasive squamous cell carcinoma are not well-understood. Here, we took a systematic approach to evaluate the neoantigens present in actinic keratosis and cutaneous squamous cell...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Antigens, Neoplasm
Share to Disease Susceptibility

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Epitope Mapping

Share to Epitopes

Share to Histocompatibility Testing

Share to HLA Antigens

Share to Lymphocytes, Tumor-Infiltrating

Share to Skin Neoplasms

Source

Open in PubMed Open full text

Identifiers

PMID: 31849976
DOI: 10.3389/fimmu.2019.02799
PMCID: PMC6896054

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Neoantigen Fitness Model Predicts Lower Immune Recognition of Cutaneous Squamous Cell Carcinomas Than Actinic Keratoses.PMID 31849976Read ↗

NeoScore integrates characteristics of the neoantigen:MHC class I interaction and expression to accurately prioritize immunogenic neoantigensSemantic proximity Read ↗

Distinct sets of molecular characteristics define tumor-rejecting neoantigensSemantic proximity Read ↗

Immunoediting restricts clonal neoantigens in primary, treatment-naive human tumors.Semantic proximity Read ↗

Influence of T Cell-Mediated Immune Surveillance on Somatic Mutation Occurrences in Melanoma.Semantic proximity Read ↗

Evolutionary dynamics of neoantigens in growing tumors.Semantic proximity Read ↗

Neoantigen quality predicts immunoediting in survivors of pancreatic cancerSemantic proximity Read ↗

Evolutionary dynamics of neoantigens in growing tumoursSemantic proximity Read ↗

Frequency-dependent selection of neoantigens fosters tumor immune escape and predicts immunotherapy responseSemantic proximity Read ↗

Neoantigen landscape dynamics during human melanoma-T cell interactions.Semantic proximity Read ↗

Frequency-dependent selection of neoantigens fosters tumor immune escape and predicts immunotherapy responseSemantic proximity Read ↗

Neoantigen evolution and response to checkpoint inhibitor immunotherapy in colorectal cancerSemantic proximity Read ↗

Analysis of thymic generation of shared T-cell receptor α repertoire associated with recognition of tumor antigens shows no preference for neoantigens over wild-type antigens.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.