Article

Neoantigen evolution and response to checkpoint inhibitor immunotherapy in colorectal cancer

2024-08-22

Abstract excerpt

<title>Abstract</title> <p>Checkpoint-blockade immunotherapy enables the patient’s immune system to recognize tumor cells that were previously invisible due to immune escape, but these therapies lead to heterogeneous patient outcomes. Focusing on colorectal cancer, in which two subtypes have markedly different responses to immunotherapy, we seek to understand how the mutagenic landscape of the tumor is related to...

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Literature Corpus work: 50c7d542-16eb-5b49-8b0f-7ea3663e6c7b
DOI: 10.21203/rs.3.rs-4922340/v1

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