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Article

An ABCG Transporter Functions in Rab Localization and Lysosome-Related Organelle Biogenesis in Caenorhabditis elegans.

Genetics - 1 Feb 2020

Voss Laura, Foster Olivia K, Harper Logan, Morris Caitlin, Lavoy Sierra, Brandt James N, Peloza Kimberly, Handa Simran, Maxfield Amanda, Harp Marie, King Brian, Eichten Victoria, Rambo Fiona M, Hermann Greg J

Abstract excerpt

ABC transporters couple ATP hydrolysis to the transport of substrates across cellular membranes. This protein superfamily has diverse activities resulting from differences in their cargo and subcellular localization. Our work investigates the role of the ABCG family member WHT-2 in the biogenesis of gut granules, a Caenorhabditis elegans lysosome-related organelle. In addition to being required for the...

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Share to ATP Binding Cassette Transporter, Subfamily G, Member 2
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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 31848222
DOI: 10.1534/genetics.119.302900
PMCID: PMC7017009

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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