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Article

Role of the Caenorhabditis elegans multidrug resistance gene, mrp-4, in gut granule differentiation.

Genetics - 1 Nov 2007

Currie Erin, King Brian, Lawrenson Andrea L, Schroeder Lena K, Kershner Aaron M, Hermann Greg J

Abstract excerpt

Caenorhabditis elegans gut granules are lysosome-related organelles with birefringent contents. mrp-4, which encodes an ATP-binding cassette (ABC) transporter homologous to mammalian multidrug resistance proteins, functions in the formation of gut granule birefringence. mrp-4(-) embryos show a delayed appearance of birefringent material in the gut granule but otherwise appear to form gut granules properly....

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 17947407
DOI: 10.1534/genetics.107.080689
PMCID: PMC2147964

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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