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Article

Function of the Caenorhabditis elegans ABC transporter PGP-2 in the biogenesis of a lysosome-related fat storage organelle.

Molecular biology of the cell - 1 Mar 2007

Schroeder Lena K, Kremer Susan, Kramer Maxwell J, Currie Erin, Kwan Elizabeth, Watts Jennifer L, Lawrenson Andrea L, Hermann Greg J

Abstract excerpt

Caenorhabditis elegans gut granules are intestine specific lysosome-related organelles with birefringent and autofluorescent contents. We identified pgp-2, which encodes an ABC transporter, in screens for genes required for the proper formation of gut granules. pgp-2(-) embryos mislocalize birefringent material into the intestinal lumen and are lacking in acidified intestinal V-ATPase-containing compartments....

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Share to ATP Binding Cassette Transporter, Subfamily B
Share to Cytoplasmic Granules

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Embryo, Nonmammalian

Share to Endocytosis

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Share to Intracellular Membranes

Share to Lipid Metabolism

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Source

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Identifiers

PMID: 17202409
DOI: 10.1091/mbc.e06-08-0685
PMCID: PMC1805080

Genes

PGP

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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