Diverse Cell Type-Specific Mechanisms Localize G Protein-Coupled Receptors to <i>Caenorhabditis elegans</i> Sensory Cilia

Abstract excerpt

The localization of signaling molecules such as G protein-coupled receptors (GPCRs) to primary cilia is essential for correct signal transduction. Detailed studies over the past decade have begun to elucidate the diverse sequences and trafficking mechanisms that sort and transport GPCRs to the ciliary compartment. However, a systematic analysis of the pathways required for ciliary targeting of multiple GPCRs in...

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