Article
Cyclooxygenase-2 Gene Polymorphisms -765G>C and -1195A>G and Mycosis Fungoides Risk.
Dermatology (Basel, Switzerland) - 1 Jan 2021
Sayed Khadiga Sayed, Mohammed Faisal Nouredin, Abdel Hay Rania Mounir, Amr Khalda Sayed, AlOrbani Aya M
Abstract excerpt
BACKGROUND: Cyclooxygenase-2 (COX-2) is an inducible modulator of inflammation that acts through increasing prostaglandin levels and has been described as a major mediator linking inflammation to cancer. Previous studies supported that COX-2-765G>C and -1195A>G polymorphisms were associated with increased risk of several solid tissue cancers as well as some hematological malignancies. OBJECTIVE: The aim of the...
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